3CLP:
an online tool for predicting coronavirus 3CL protease cleavage sites
This table shows the known cleavage sites of the 3CL protease on polyprotein ORF1ab which were obtained from 14 coronavirus species in three genera:
Genus
Species
Accession number
Definition
Cleavage sites
.
The predicted cleavage sites on human proteins(taking 0.5 as cutoff), were available for downloading here.
The predicted cleavage sites on human proteins(score=1) are listed in the following table:
Uniprot ID
Position of Q (Gln)
Motif
The training data for 3CLP, which included 265 positive and negative cleavage motifs respectively, were available for downloading here. For more details about the training data, please refer to our study.
The testing data for 3CLP, which included 105 positive and 6326 negative cleavage motifs respectively, were available for downloading here. For more details about the testing data, please refer to our study.